产品信息
| 规格 | 100μg/支 |
| 货号 | Gab-202201 |
| 反应物种 | Human, Mouse, Rat, Other (Wide Range) |
| 产品应用 | DB |
| 推荐稀释比 | DB 1:500 - 1:2000 |
| 存储缓冲液 | Store at -20℃. Avoid freeze / thaw cycles. |
| Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. | |
| 纯化方式 | Affinity purification |
抗原信息
| 免疫原 | Chemical compounds corresponding to N6-methyladenosine / m6A. |
| 序列 | Email for sequence |
靶点信息
Discovered in the 1970s, m6A is the most prevalent internal modification in polyadenylated mRNAs and long non-coding RNAs (lncRNAs) in higher eukaryotes. m6A is widely conserved among eukaryotic species that range from yeast, plants, flies to mammals, as well as among viral RNAs with a nuclear phase. The m6A-based modification is associated with a well-defined RNA motif, RRACH (R: A/G, H: A/C/U). As a representative of the epitranscriptome, m6A mRNA modifications participate in many vital activities in the cell, including stem cell self-renewal and differentiation, mRNA transcription, alternative splicing, nuclear export, translation, degradation, and microRNA processing. These processes determine the expression or inactivation of specific genes, which is vital for growth and development.(PMID: 30416848; PMID: 24662220; PMID: 30429466)
| RRID | AB_2862629 |
| 别名 | N6-methyladenosine;m6A |
